The growth in the number, size, and production capability of salmon and other fish farms in the past twenty-five years has led to demands for national regulation of fish farm effluents. Pollution from salmon and other fish farms is substantial and reuslts in numerous adverse environmental effects. Existing laws do not effectively control discharges from salmon fish farms and other aquaculture facilities. This Comment argues that the Environmental Protection Agency should promulgate aquaculture industry effluent limitations to ensure consistent regulation of fish farms. The implementation of effluent limitations will facilitate the issuance of National Pollution Discharge Elimination System permits and lead to a reduction in discharged pollutants from fish farms.